BRCA and Genetic Screening at The London Breast Clinic

BRACAnalysis – A test for hereditary breast and ovarian cancer (HBOC) syndrome.




Breast and Ovarian Cancer that runs in the family can occur because of a mutation or alteration in the BRCA1 or BRCA2 genes. If you have a BRCA gene mutation you could have up to an 87% risk of developing breast cancer and up to a 44% risk of developing ovarian cancer in your lifetime.

You may be suitable for the test if you have in either your personal or family history;

  • Ovarian cancer
  • Breast cancer diagnosed at less than 50 years old
  • Two primary breast cancers in the same individual
  • Two individuals with breast cancer on the same side of the family
  • Male breast cancer
  • Triple negative breast cancer
  • Pancreatic cancer with an additional HBOC associated cancer
  • Ashkenazi Jewish ancestry with an HBOC associated cancer
  • A previously identified BRCA mutation in the family

The tests are;

  • Comprehensive BRCAnalysis offered to all families with no known mutation.
  • Single site BRCAnalysis offered to families in which there is a known pathogenic (disease causing) mutation.
  • Multi-site 3 BRCAnalysis offered to individuals of Jewish heritage who may have cancer themselves or may be unaffected.

Please click on the Myriad logo to download an information booklet.




Please click on the My Risk logo to download an information booklet.




The process would involve a consultation with Dr James Mackay, Consultant Clinical Genetic Oncologist to discuss your personal risk profile together with pros and cons of undergoing the test.

If after the consultation you wish to proceed with the test then blood for analysis can be taken at that visit.

It may be that the test is not suitable for you but it is possible to undertake surveillance such as mammography or ovarian screening if appropriate.

The costs associated with the test and screening are as follows

Initial Consultation with Dr Mackay - £350

Follow up Consultation with Dr Mackay - £125

Single site BRCAnalysis  - £254

Multi-site 3 BRCAnalysis  - £309

Integrated BRCA Analysis - £2,238

Phlebotomy charge  - £20

Mammography  - £206

Breast ultrasound  - £206

Ovarian Screening – Trans-vaginal ultrasound and CA 125 monitoring  - £550

Even if you have medical insurance, charges for screening are not routinely covered by medical insurers but some may consider it on a case by case basis because of personal and family history if you contact in advance for pre-authorisation You will be asked to pay all charges on the day, unless you can provide confirmation of full cover, but receipts will be provided for you to submit for reimbursement if this is not available.

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